DNAcycP: a deep learning tool for DNA cyclizability prediction
Measuring intrinsic DNA cyclizability/bendability experimentally (via loop-seq) is laborious; a fast computational predictor was needed.
510 of 510 verified cases.
Measuring intrinsic DNA cyclizability/bendability experimentally (via loop-seq) is laborious; a fast computational predictor was needed.
Manual assessment of surgeons' skills is time-consuming, subjective and prone to inconsistent interpretation.
Manually labeling camera trap images of mammals for wildlife monitoring is slow and hard to scale; the paper automates species identification in Białowieża Forest, Poland.
Predicting the short-term evolution and long-term statistics of a multiscale chaotic Lorenz 96 system when only the large-scale variables are observable and the smaller-scale processes are never known.
Automatic speech recognizers perform poorly on dysarthric speech, making voice technology unreliable for affected speakers.
Identifying drug-target interactions experimentally is costly and labor-intensive, and conventional protein descriptors were insufficiently informative for accurate in silico prediction.
Optimizing molecules for drug discovery, including maximizing drug-likeness while maintaining similarity to an original molecule during medicinal chemistry lead optimization.
Conservationists need to automatically identify and classify wildlife species in large camera-trap image datasets, which is slow and error-prone manually.
Gravitational-wave interferometers like advanced LIGO produce transient noise signals (glitches) that must be classified and separated from real astrophysical signals.
Whether deep learning can emulate the dynamics of weather and climate general circulation models to enable data-driven forecasting.
Accurately predicting 8-state protein secondary structure, which serves as an information bridge between primary sequence and tertiary structure for structure-based analysis.
Astronomers needed a systematic, unbiased way to classify Type II supernova light curves ahead of upcoming large transient surveys.
Tire defects such as cracks and debris are hard to detect manually, creating safety risks and labor costs for drivers and manufacturers.
Superresolution photoacoustic imaging achieves very high spatial resolution but requires superimposing many raw image frames, sacrificing temporal resolution and making imaging slow.
The claustrum's delicate, sheet-like structure made it infeasible to segment with conventional methods in human brain MRI, limiting in vivo research.
Multiple robots working in narrow, confined environments suffer congestion and interference that hinder collective task performance, and coordinating them without explicit communication is hard.
Stitched fluorescence microscope images contain stripes and artifacts from optics or specimens that degrade image quality and ruin downstream quantitative analysis.
New energy vehicle enterprises need accurate demand forecasting as a decision-making basis.
Inverse design of transonic airfoils—finding a shape that produces a prescribed pressure distribution—is computationally slow.
Designing synthetic copolymers that stabilize proteins is difficult because the chemical and composition space is too vast for rational design.
Predicting grapevine yield early in the season across different varieties to support wine industry yield assessment.
3D particle reconstruction from limited 2D projections in volumetric PIV is an under-determined inverse problem that iterative methods solve only approximately.
Finding optimal machine settings for the plasticizing process in injection molding normally requires time-consuming, expensive physical trials.
Batches of the same specified material differ in machinability, and unidentified differences reduce product quality and raise manufacturing costs.