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Machine learning applications on neonatal sepsis treatment: a scoping review

Colleen O’Sullivan, Daniel Hsiang‐Te Tsai, Ian Chang-Yen Wu, Emanuela Boselli, Carmel M Hughes, Deepak Padmanabhan, Yingfen Hsia

BMC Infectious Diseases 2023 cited by 29

Medicine & Health Neonatal and Maternal Infections ai assisted importance 7/10 scale stated

Neonatal sepsis has non-specific signs, treatment is labour-intensive, and antimicrobial resistance complicates empiric antibiotic choice.

Details Source Open-access PDF model: not stated in source

Quantum Error Correction with Quantum Autoencoders

David F. Locher, Lorenzo Cardarelli, Markus Michael Müller

Quantum 2023 cited by 36

Physics & Astronomy Quantum Computing Algorithms and Architecture ai assisted importance 7/10 scale stated

Quantum processors require active error correction, and designing effective strategies for detecting and correcting varied errors (including correlated errors and qubit loss) is difficult.

Details Source Open-access PDF model: Quantum autoencoders (quantum neural netwo...

The Immune Subtypes and Landscape of Gastric Cancer and to Predict Based on the Whole-Slide Images Using Deep Learning

Yan Chen, Zepang Sun, Wanlan Chen, Changyan Liu, Ruoyang Chai, Jingjing Ding, Wen Liu, Xianzhen Feng et al.

Frontiers in Immunology 2021 cited by 71

Medicine & Health Cancer Immunotherapy and Biomarkers ai assisted importance 7/10 scale stated

Gastric cancer responds heterogeneously to immunotherapy, and identifying immune subtypes could improve therapeutic strategies.

Details Source Open-access PDF model: not stated in source

Malaria parasite detection in thick blood smear microscopic images using modified YOLOV3 and YOLOV4 models

Fetulhak Abdurahman, Kinde Anlay Fante, Mohammed Aliy Mohammed

BMC Bioinformatics 2021 cited by 139

Medicine & Health Digital Imaging for Blood Diseases ai assisted importance 7/10 scale stated

Manual microscopic examination of blood smears, the gold standard for malaria diagnosis, depends on skilled microscopists who are scarce in remote developing regions.

Details Source Open-access PDF model: Modified YOLOv3 and YOLOv4

An overview and metanalysis of machine and deep learning-based CRISPR gRNA design tools

Jun Wang, Xiuqing Zhang, Lixin Cheng, Yonglun Luo

RNA Biology 2019 cited by 102

Biology & Life Sciences CRISPR and Genetic Engineering ai assisted importance 7/10 scale stated

Predicting the on-target activity and off-target specificity of CRISPR-Cas9 guide RNAs is difficult, yet decisive for safe and effective gene editing.

Details Source Open-access PDF model: various machine and deep learning models (...

Advances in De Novo Drug Design: From Conventional to Machine Learning Methods

Varnavas D. Mouchlis, Antreas Afantitis, Angela Serra, Michele Fratello, Anastasios G. Papadiamantis, Vassilis Aidinis, Iseult Lynch, Dario Greco et al.

International Journal of Molecular Sciences 2021 cited by 352

Medicine & Health Computational Drug Discovery Methods ai assisted importance 7/10 scale stated

De novo drug design, generating novel molecular structures from atomic building blocks, is difficult and costly with conventional structure- or ligand-based methods.

Details Source Open-access PDF model: deep reinforcement learning with RNNs, CNN...

Applications of artificial intelligence in clinical laboratory genomics

Swaroop Aradhya, Flavia M. Facio, Hillery C. Metz, Toby R. Manders, Alexandre Colavin, Yuya Kobayashi, Keith Nykamp, Britt A. Johnson et al.

American Journal of Medical Genetics Part C Seminars in Medical Genetics 2023 cited by 56

Medicine & Health Artificial Intelligence in Healthcare and Education ai assisted importance 7/10 scale stated

Genomic data volumes are exceeding human capacity to rapidly and reproducibly analyze complex molecular data for timely diagnosis and management of genomic disorders.

Details Source Open-access PDF model: not stated in source

Superhuman AI for multiplayer poker

Noam Brown, Tüomas Sandholm

Science 2019 cited by 583

Mathematics Artificial Intelligence in Games solved importance 6/10 scale stated

AI had surpassed humans in two-player games, but six-player no-limit Texas hold'em poker remained a much harder, unsolved challenge.

Details Source model: Pluribus

An autonomous laboratory for the accelerated synthesis of inorganic materials

Nathan J. Szymanski, Bernardus Rendy, Yuxing Fei, Rishi E. Kumar, Tanjin He, David Milsted, Matthew J. McDermott, Max C. Gallant et al.

Nature 2023 cited by 999

Engineering & Materials Machine Learning in Materials Science solved importance 6/10 scale stated

Synthesizing novel inorganic materials is slow and labor-intensive; the work aimed to autonomously accelerate solid-state synthesis of targeted compounds.

Details Source Open-access PDF model: A-Lab (ML, active learning, natural-langua...

Identification of nanomolar adenosine A2A receptor ligands using reinforcement learning and structure-based drug design

Morgan C. Thomas, Pierre G. Matricon, Robert F. Gillespie, Maja Napiórkowska, Hannah Neale, Jonathan S. Mason, Jason Brown, Kaan Harwood et al.

Nature Communications 2025 cited by 24

Biology & Life Sciences Computational Drug Discovery Methods solved importance 6/10 scale stated

Finding novel small-molecule ligands for the adenosine A2A receptor from protein structure alone, without prior knowledge of ligand chemistry.

Details Source Open-access PDF model: Generative chemical language models with A...

Combinatorial Optimization-Enriched Machine Learning to Solve the Dynamic Vehicle Routing Problem with Time Windows

Léo Baty, Kai Jungel, Patrick S. Klein, Axel Parmentier, Maximilian Schiffer

Transportation Science 2024 cited by 69

Business & Industry Vehicle Routing Optimization Methods solved importance 6/10 scale stated

Logistics providers struggle to plan same-day deliveries: stochastic optimization is too slow online and reinforcement learning struggles with high-dimensional combinatorial problems.

Details Source Open-access PDF model: ML pipeline with combinatorial optimizatio...

Protein structure prediction with in-cell photo-crosslinking mass spectrometry and deep learning

Kolja Stahl, Andrea Graziadei, Therese Dau, Oliver Brock, Juri Rappsilber

Nature Biotechnology 2023 cited by 161

Biology & Life Sciences Protein Structure and Dynamics partially solved importance 6/10 scale stated

Predicting accurate structures for challenging proteins, such as those undergoing conformational changes or with few homologous sequences, where AlphaFold2 underperforms.

Details Source Open-access PDF model: AlphaLink (modified AlphaFold2)

Incorporating the image formation process into deep learning improves network performance

Yue Li, Yijun P. Su, Min Yi Guo, Xiaofei Han, Jiamin Liu, Harshad D. Vishwasrao, Xuesong Li, Ryan Patrick Christensen et al.

Nature Methods 2022 cited by 123

Science & Research Advanced Image Processing Techniques solved importance 6/10 scale stated

Deconvolution of 3D fluorescence microscopy images is slow and artifact-prone with existing methods.

Details Source Open-access PDF model: Richardson-Lucy network (RLN), fully convo...

MMSplice: modular modeling improves the predictions of genetic variant effects on splicing

Jun Cheng, Thi Yen Duong Nguyen, Kamil J. Cygan, Muhammed Hasan Çelik, William Guy Fairbrother, Žiga Avsec, Julien Gagneur

Genome biology 2019 cited by 234

Biology & Life Sciences RNA Research and Splicing solved importance 6/10 scale stated

Predicting how genetic variants affect splicing (exon skipping, splice site choice, pathogenicity) is difficult but highly relevant to human genetics.

Details Source Open-access PDF model: MMSplice (modular neural networks)

SpCas9 activity prediction by DeepSpCas9, a deep learning–based model with high generalization performance

Hui Kwon Kim, Younggwang Kim, Sungtae Lee, Seonwoo Min, Jung Yoon Bae, Jae Woo Choi, Jinman Park, Dongmin Jung et al.

Science Advances 2019 cited by 237

Biology & Life Sciences CRISPR and Genetic Engineering solved importance 6/10 scale stated

Predicting SpCas9 gene-editing activity at arbitrary target sequences was unreliable, limiting CRISPR-based editing.

Details Source Open-access PDF model: DeepSpCas9