Implementation of large language models in electronic health records

Maxime Griot, Jean M. Vanderdonckt, Demet Yüksel

PLOS Digital Health 2025 article cited by 22

importance 6/10 ai assisted Artificial Intelligence in Healthcare and Education clinical documentation stage: deployed open-source model

Electronic health records have increased clinicians' documentation workload, and real-world LLM deployments in live hospital systems remain limited.

Documentation burden takes clinicians' time away from patient care in hospitals.

A secure, GDPR-compliant, on-premises LLM assistant with retrieval augmented generation was integrated into the Epic EHR to give context-aware answers from patient data, clinical documents, and medical literature.

One-month pilot with 28 physicians across nine specialties: 64% used it daily, 482 multi-turn conversations; summarization, information retrieval, and note drafting were over 70% of interactions; hospital-wide deployment followed.

The pilot showed high physician engagement and the system was subsequently deployed hospital-wide.

Venue PLOS Digital Health
Published 2025
Work type article
Authors Maxime Griot, Jean M. Vanderdonckt, Demet Yüksel
Citations 22 (OpenAlex, at import time)
References 27
Model or method Qwen3-235B with Retrieval Augmented Generation
Organization not stated in source
Primary source https://doi.org/10.1371/journal.pdig.0001141
Open access gold
Keywords LLM, EHR, RAG, clinical documentation, hospital deployment, Qwen3
6 / 10

significant — thousands to millions affected

Documentation burden takes clinician time from patient care; abstract quantifies deployment (1,028 users, 14,910 conversations) but not problem scale. Hospital-wide deployment shows real, significant benefit at one hospital.

Basis: inferred. Judged from the source text, which gives no explicit scale. Stated scale: not stated in source. Method and limits.

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