Democratising deep learning for microscopy with ZeroCostDL4Mic

Lucas von Chamier, Romain F. Laine, Johanna Jukkala, Christoph K. Spahn, Daniel Krentzel, Elias Nehme, Martina Lerche, Sara Hernández‐Pérez et al.

Nature Communications 2021 article cited by 524

importance 6/10 partially solved Cell Image Analysis Techniques microscopy/bioimaging stage: research open-source model

Novice researchers faced accessibility barriers to training deep learning networks for microscopy due to computational resource and coding requirements.

Removing cost and coding barriers lets non-experts apply deep learning analysis to microscopy data.

ZeroCostDL4Mic is a free Google Colab-based platform enabling users with no coding expertise to train and apply DL networks for segmentation, object detection, denoising, super-resolution, and image-to-image translation, with quantitative evaluation tools.

not stated in source

The platform lowers accessibility barriers to deep learning for microscopy, per the authors.

Venue Nature Communications
Published 2021
Work type article
Authors Lucas von Chamier, Romain F. Laine, Johanna Jukkala, Christoph K. Spahn, Daniel Krentzel, Elias Nehme, Martina Lerche, Sara Hernández‐Pérez et al.
Citations 524 (OpenAlex, at import time)
References 121
Model or method U-Net, StarDist, YOLOv2, CARE, Noise2Void, Deep-STORM, fnet, pix2pix, CycleGAN
Organization not stated in source
Primary source https://doi.org/10.1038/s41467-021-22518-0
Open access gold
Keywords deep learning, microscopy, Google Colab, segmentation, denoising
6 / 10

significant — thousands to millions affected

Removes cost/coding barriers so non-experts can apply deep learning to microscopy; broad enablement of biological research, though abstract gives no scale numbers.

Basis: inferred. Judged from the source text, which gives no explicit scale. Stated scale: not stated in source. Method and limits.

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