Deep learning based domain adaptation for mitochondria segmentation on EM volumes

Daniel Franco-Barranco, Julio Pastor-Tronch, Aitor González-Marfil, Arrate Muñoz‐Barrutia, Ignacio Arganda‐Carreras

Computer Methods and Programs in Biomedicine 2022 article cited by 24

importance 4/10 partially solved Domain Adaptation and Few-Shot Learning neuroscience imaging stage: research open-source model

Deep learning models for mitochondria segmentation in electron microscopy volumes need large annotated datasets and perform poorly on EM data from different tissues or species (domain shift).

Accurate organelle-level segmentation is essential to characterize neuronal structures, and annotating large EM datasets is costly.

The paper presents three unsupervised deep-learning domain adaptation strategies to improve mitochondria segmentation on target-domain EM datasets.

not stated in source

Proposed strategies to improve cross-dataset mitochondria segmentation; broader impact not stated in source.

Venue Computer Methods and Programs in Biomedicine
Published 2022
Work type article
Authors Daniel Franco-Barranco, Julio Pastor-Tronch, Aitor González-Marfil, Arrate Muñoz‐Barrutia, Ignacio Arganda‐Carreras
Citations 24 (OpenAlex, at import time)
References 92
Model or method not stated in source
Organization not stated in source
Primary source https://doi.org/10.1016/j.cmpb.2022.106949
Open access hybrid
Keywords deep learning, domain adaptation, mitochondria segmentation, electron microscopy, unsupervised
4 / 10

real but narrower advance

Domain adaptation for mitochondria segmentation across tissues/species reduces annotation burden for EM brain volumes; real but narrow organelle-segmentation advance.

Basis: inferred. Judged from the source text, which gives no explicit scale. Stated scale: not stated in source. Method and limits.

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