A deep learning model for detection of Alzheimer's disease based on retinal photographs: a retrospective, multicentre case-control study

Carol Yim-lui Cheung, An Ran Ran, Shujun Wang, Victor T.T. Chan, Kaiser Sham, Saima Hilal, Narayanaswamy Venketasubramanian, Ching‐Yu Cheng et al.

The Lancet Digital Health 2022 article cited by 264

importance 7/10 partially solved Retinal Imaging and Analysis dementia screening stage: research

No simple screening model exists for Alzheimer's disease; diagnosis relies on expensive, sometimes invasive tests unavailable outside specialised settings.

Cheap, non-invasive screening could widen access to early Alzheimer's detection.

A deep learning algorithm was trained, validated, and tested on retinal photographs from 11 studies across countries to detect Alzheimer's disease-dementia.

not stated in source

The study shows retinal photographs may support Alzheimer's screening, pending further validation.

Venue The Lancet Digital Health
Published 2022
Work type article
Authors Carol Yim-lui Cheung, An Ran Ran, Shujun Wang, Victor T.T. Chan, Kaiser Sham, Saima Hilal, Narayanaswamy Venketasubramanian, Ching‐Yu Cheng et al.
Citations 264 (OpenAlex, at import time)
References 29
Model or method bilateral deep learning model
Organization not stated in source
Primary source https://doi.org/10.1016/s2589-7500(22)00169-8
Open access gold
Keywords deep learning, Alzheimer's disease, retinal photographs, screening, dementia detection
7 / 10

significant — thousands to millions affected

Cheap, non-invasive Alzheimer's screening could widen access beyond specialized settings; major disease but abstract gives no scale.

Basis: inferred. Judged from the source text, which gives no explicit scale. Stated scale: not stated in source. Method and limits.

# Paper Year Citations Importance
1 Multimodal deep learning of fundus abnormalities and traditional risk factors for cardiovascular risk prediction
Yeong Chan Lee, Jiho Cha, Injeong Shim, Woong‐Yang Park, Se Woong Kang...
2023 107
10
2 Reliable Tuberculosis Detection Using Chest X-Ray With Deep Learning, Segmentation and Visualization
Tawsifur Rahman, Amith Abdullah Khandakar, Muhammad Abdul Kadir, Khand...
2020 651
10
3 A comparative analysis of machine learning classifiers for stroke prediction: A predictive analytics approach
Nitish Biswas, Khandaker Mohammad Mohi Uddin, Sarreha Tasmin Rikta, Sa...
2022 116
10
4 Cardiovascular Disease Diagnosis from DXA Scan and Retinal Images Using Deep Learning
Hamada R. H. Al-Absi, Mohammad Tariqul Islam, Mahmoud Ahmed Refaee, Mu...
2022 89
10
5 Proteomics and Machine Learning Approaches Reveal a Set of Prognostic Markers for COVID-19 Severity With Drug Repurposing Potential
Kruthi Suvarna, Deeptarup Biswas, Medha Gayathri J. Pai, Arup Acharjee...
2021 76
10